Spoiler alert: Pacino talks about the character, the aging actor (a part he can relate to) who tries to commit suicide at the beginning of the book. He also gives away the ending, of the book and I assume the movie. So if you haven't read the book, you may want to hang back.
The Humbling stars Al Pacino as washed-up actor Simon Axler, Greta Gerwig as the young lesbian who falls for him with Dianne Weist and Charles Grodin as her parents along with Kyra Sedgework and Dylan Baker. Directed by Barry Levinson, the script was written by Buck Henry.